study summary / 017

Can neighborhood greenery shape a child's developing brain?

A longitudinal MRI study of 7,102 children links residential vegetation with cortical development, but does not establish causation.

A child grows up between walls, streets and the trees outside the window. I often ask myself what that green does to a brain that is still being built. A large study from the United States followed thousands of children and looked for an answer.

The study

Li, Whittle and Rakesh analyzed 7,102 children in the ABCD cohort, initially aged 9–10. Residential greenery was estimated with the normalized difference vegetation index (NDVI). Structural MRI was assessed about two years later, including changes over time. Models adjusted for household income relative to needs and neighborhood deprivation.

Measured results

Greater greenery was associated with greater total cortical surface area (B = 0.046, SE = 0.012, p < 0.001) and total cortical volume (B = 0.049, SE = 0.012, p < 0.001). Regional thickness associations differed in direction. Greater greenery was also associated with larger caudate, putamen and nucleus accumbens volumes. Over time, it was linked to greater growth in total surface area and smaller growth in total cortical volume. According to the abstract, indirect associations through cortical structure were significant for both academic performance and mental health. For academic performance, the indirect association through total cortical surface area was 0.004 (95% CI 0.002–0.007), while the total association was not significant (p = 0.985).

Why it matters for architecture

For me, a tree outside a child's window is architecture too. Where we plant, how much, and how close to home are design decisions. This study does not prove that greener streets build better brains. It tells me that greenery belongs in the plan from the beginning, and that we should measure what it does, not assume it.

Limits and PhD question

This observational study cannot show that adding trees changes the brain. NDVI does not measure use or quality of green space. MRI cannot count synapses. Importantly, study site explained substantial variation in greenery and adjusting for site weakened several findings. A future intervention with comparison neighborhoods could test whether deliberately improving green space changes health or brain outcomes.

original study

Li, Whittle & Rakesh (2025/2026)
Longitudinal Associations Between Greenspace Exposure, Structural Brain Development, and Mental Health and Academic Performance During Early Adolescence. Biological Psychiatry, 99(4), 286–298.

doi: 10.1016/j.biopsych.2025.03.026